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Ret Proto-Oncogene 抗体 (pTyr1062)

This 兔 多克隆 anti-Ret Proto-Oncogene antibody specifically detects Ret Proto-Oncogene in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7223992
发货至: 中国
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Quick Overview for Ret Proto-Oncogene 抗体 (pTyr1062) (ABIN7223992)

抗原

See all Ret Proto-Oncogene (RET) 抗体
Ret Proto-Oncogene (RET)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Ret Proto-Oncogene antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr1062

    原理

    Ret (phospho Tyr1062) Polyclonal Antibody

    特异性

    Phospho-Ret (Y1062) Polyclonal Antibody detects endogenous levels of Ret protein only when phosphorylated at Y1062.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Ret Phospho-Tyr1062

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Ret Proto-Oncogene (RET)

    别名

    Ret

    背景

    Rabbit Anti-Ret (phospho Tyr1062) Polyclonal Antibody,RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret,RET (ret proto-oncogene), a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in RET are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for RET. Additional transcript variants have been described but their biological validity has not been confirmed.,Proto-oncogene tyrosine-protein kinase receptor Ret

    分子量

    observerd band 170kDa

    基因ID

    5979

    UniProt

    P07949

    途径

    RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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