PDK3 抗体 (AA 170-250)
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Quick Overview for PDK3 抗体 (AA 170-250) (ABIN7230570)
抗原
See all PDK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-250
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原理
- PDK3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PDK3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PDK3 protein at AA range: 170-250
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibody
PDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibodyPDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 137-406) antibodyPDK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (Center) antibodyPDK3 适用: 人 ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB23090 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 1-30), (N-Term) antibodyPDK3 适用: 人 WB 宿主: 兔 Polyclonal RB3039 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (N-Term) antibodyPDK3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 131-362) antibodyPDK3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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别名
- PDK3
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背景
- Rabbit Anti-PDK3 Polyclonal Antibody,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial , Pyruvate dehydrogenase kinase isoform 3,The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by PDK3 (Pyruvate Dehydrogenase Kinase 3) is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. PDK3 is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for PDK3.,PDK3
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分子量
- observerd band 44kDa
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基因ID
- 5165
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UniProt
- Q15120
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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