PDK2 抗体 (AA 230-310)
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Quick Overview for PDK2 抗体 (AA 230-310) (ABIN7216486)
抗原
See all PDK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-310
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原理
- PDK2 Polyclonal Antibody
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特异性
- PDK2 Polyclonal Antibody detects endogenous levels of PDK2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human PDK2 at AA range: 230-310
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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别名
- PDK2
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背景
- Rabbit Anti-PDK2 Polyclonal Antibody,PDK2, PDHK2, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2,PDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2 mitochondrial
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分子量
- observerd band 46kDa
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基因ID
- 5164
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UniProt
- Q15119
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途径
- PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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