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PKC theta 抗体 (pSer695)

This 兔 多克隆 anti-PKC theta antibody specifically detects PKC theta in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7223554
发货至: 中国
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Quick Overview for PKC theta 抗体 (pSer695) (ABIN7223554)

抗原

See all PKC theta (PRKCQ) 抗体
PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC theta antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pSer695

    原理

    PKC θ (phospho Ser695) Polyclonal Antibody

    特异性

    Phospho-PKC θ (S695) Polyclonal Antibody detects endogenous levels of PKC θ protein only when phosphorylated at S695.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PKC theta Phospho-Ser695

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

    别名

    PKC theta

    背景

    Rabbit Anti-PKC θ (phospho Ser695) Polyclonal Antibody,PRKCQ, PRKCT, Protein kinase C theta type, nPKC-theta,Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by PRKCQ (protein kinase C theta) is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.,Protein kinase C theta type

    分子量

    observerd band 85kDa

    基因ID

    5588

    UniProt

    Q04759

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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