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PAPPA 抗体 (AA 30-110)

This 兔 多克隆 anti-PAPPA antibody specifically detects PAPPA in ELISA 和 WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7230486
发货至: 中国
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Quick Overview for PAPPA 抗体 (AA 30-110) (ABIN7230486)

抗原

See all PAPPA 抗体
PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

适用

人, 小鼠

宿主

  • 65
  • 46
  • 1

克隆类型

  • 66
  • 46
多克隆

标记

  • 44
  • 14
  • 11
  • 8
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAPPA antibody is un-conjugated

应用范围

  • 51
  • 49
  • 33
  • 31
  • 13
  • 13
  • 10
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-110

    原理

    PAPP1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PAPP1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PAPP1 protein at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

    别名

    PAPP1

    背景

    Rabbit Anti-PAPP1 Polyclonal Antibody,Insulin-like growth factor-dependent IGF-binding protein 4 protease, IGF-dependent IGFBP-4 protease, IGFBP-4ase, Pregnancy-associated plasma protein A, PAPP-A,PAPPA encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers.,PAPP1

    分子量

    observerd band 178kDa

    基因ID

    5069

    UniProt

    Q13219
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