PAK4 抗体
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北京 101111
Quick Overview for PAK4 抗体 (ABIN7218956)
抗原
See all PAK4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PAK4/5/6 Polyclonal Antibody
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特异性
- PAK4/5/6 Polyclonal Antibody detects endogenous levels of PAK4/5/6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human PAK4 around the non-phosphorylation site of S474
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PAK4 (P21-Activated Kinase 4 (PAK4))
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别名
- PAK4/5/6
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背景
- Rabbit Anti-PAK4/5/6 Polyclonal Antibody,PAK4, KIAA1142, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4,PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK5 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,serine threonine-protein kinase PAK 4
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分子量
- observerd band 80kDa
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基因ID
- 10298
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UniProt
- O96013
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途径
- RTK signaling
抗原
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