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NCOR2 抗体 (AA 480-560)

This 兔 多克隆 antibody specifically detects NCOR2 in ELISA, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7226048
发货至: 中国
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Quick Overview for NCOR2 抗体 (AA 480-560) (ABIN7226048)

抗原

See all NCOR2 抗体
NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

适用

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宿主

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克隆类型

  • 40
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多克隆

标记

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This NCOR2 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 480-560

    原理

    SMRTe Polyclonal Antibody

    特异性

    SMRTe Polyclonal Antibody detects endogenous levels of SMRTe protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human SMRTe at AA range: 480-560

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

    别名

    SMRTe

    背景

    Rabbit Anti-SMRTe Polyclonal Antibody,NCOR2, CTG26, Nuclear receptor corepressor 2, N-CoR2, CTG repeat protein 26, SMAP270, Silencing mediator of retinoic acid and thyroid hormone receptor, SMRT, T3 receptor-associating factor, TRAC, Thyroid-, retinoic-acid-receptor-associated,NCOR2 (nuclear receptor corepressor 2) encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of NCOR2 is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.,Nuclear receptor corepressor 2

    分子量

    observerd band 270kDa

    基因ID

    9612

    UniProt

    Q9Y618

    途径

    Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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