NBR1 抗体
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北京 101111
Quick Overview for NBR1 抗体 (ABIN7212362)
抗原
See all NBR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Anti-NBR1 Mouse Monoclonal Antibody (7C3)
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特异性
- The antibody detects endogenous NBR1 protein.
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纯化方法
- The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Recombinant Protein of NBR1
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亚型
- IgG1
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anti-Neighbor of BRCA1 Gene 1 (NBR1) antibody
NBR1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-96) antibodyNBR1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-96) antibodyNBR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B11 unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) antibodyNBR1 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-96) antibodyNBR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 1-966) antibodyNBR1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 1-966) antibodyNBR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (C-Term) antibodyNBR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 1-280) antibodyNBR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) antibodyNBR1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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别名
- NBR1
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背景
- Next to BRCA1 gene 1 protein, Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3BThe protein encoded by NBR1 (NBR1, autophagy cargo receptor) was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of NBR1 results in multiple transcript variants.
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分子量
- 120kD
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基因ID
- 4077
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UniProt
- Q14596
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途径
- Autophagy
抗原
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