NADPH Oxidase 4 抗体
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北京 101111
Quick Overview for NADPH Oxidase 4 抗体 (ABIN7230064)
抗原
See all NADPH Oxidase 4 (NOX4) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NOX4 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of NOX4 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human NOX4 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NADPH Oxidase 4 (NOX4)
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别名
- NOX4
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背景
- Rabbit Anti-NOX4 Polyclonal Antibody,NADPH oxidase 4, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase,NOX4 gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.,NOX4
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分子量
- observerd band 63kDa
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基因ID
- 50507
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UniProt
- Q9NPH5
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途径
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
抗原
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