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MYLK 抗体 (pTyr464)

This 兔 多克隆 antibody specifically detects MYLK in ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7222614
发货至: 中国
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Quick Overview for MYLK 抗体 (pTyr464) (ABIN7222614)

抗原

See all MYLK 抗体
MYLK (Myosin Light Chain Kinase (MYLK))

适用

  • 73
  • 51
  • 45
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  • 1
  • 1

宿主

  • 81
  • 4
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  • 1

克隆类型

  • 66
  • 23
多克隆

标记

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  • 1
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  • 1
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This MYLK antibody is un-conjugated

应用范围

  • 51
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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 8
    • 5
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    • 2
    • 2
    • 1
    • 1
    • 1
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    pTyr464

    原理

    MYLK (phospho Tyr464) Polyclonal Antibody

    特异性

    Phospho-MYLK (Y464) Polyclonal Antibody detects endogenous levels of MYLK protein only when phosphorylated at Y464.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human MYLK Phospho-Tyr464

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MYLK (Myosin Light Chain Kinase (MYLK))

    别名

    MYLK

    背景

    Rabbit Anti-MYLK (phospho Tyr464) Polyclonal Antibody,MYLK, MLCK, MLCK1, MYLK1, Myosin light chain kinase, smooth muscle, MLCK, s mMLCK, Kinase-related protein, KRP, Telokin,MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.,Myosin light chain kinase smooth muscle

    基因ID

    4638

    UniProt

    Q15746
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