GANP 抗体 (AA 1810-1890)
Quick Overview for GANP 抗体 (AA 1810-1890) (ABIN7225706)
抗原
See all GANP (MCM3AP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1810-1890
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原理
- GANP Polyclonal Antibody
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特异性
- GANP Polyclonal Antibody detects endogenous levels of GANP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human GANP at AA range: 1810-1890
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
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别名
- GANP
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背景
- Rabbit Anti-GANP Polyclonal Antibody,MCM3AP, GANP, KIAA0572, MAP80, 80 kDa MCM3-associated protein, Protein GANP,The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by MCM3AP (minichromosome maintenance complex component 3 associated protein) is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. MCM3AP is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.,80 kDa MCM3-associated protein
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分子量
- observerd band 218kDa
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基因ID
- 8888
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UniProt
- O60318
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途径
- Protein targeting to Nucleus
抗原
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