MMP14 抗体 (AA 440-520)
Our Local Distributor
北京 101111
Quick Overview for MMP14 抗体 (AA 440-520) (ABIN7222512)
抗原
See all MMP14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 440-520
-
原理
- MMP-14 Polyclonal Antibody
-
特异性
- MMP-14 Polyclonal Antibody detects endogenous levels of MMP-14 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human MMP-14 at AA range: 440-520
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
-
别名
- MMP-14
-
背景
- Rabbit Anti-MMP-14 Polyclonal Antibody,MMP14, Matrix metalloproteinase-14, MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP,Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by MMP14 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.,Matrix metalloproteinase-14
-
分子量
- observerd band 65kDa
-
基因ID
- 4323
-
UniProt
- P50281
-
途径
- Autophagy
抗原
-