MKNK2 抗体 (Internal Region)
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Quick Overview for MKNK2 抗体 (Internal Region) (ABIN7221276)
抗原
See all MKNK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Mnk2 Polyclonal Antibody
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特异性
- Mnk2 Polyclonal Antibody detects endogenous levels of Mnk2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Mnk2
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亚型
- IgG
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anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-158) antibody
MKNK2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-158) antibodyMKNK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F11 unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 36-85) antibodyMKNK2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 41-158) antibodyMKNK2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (N-Term) antibodyMKNK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-100) antibodyMKNK2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (Internal Region) antibodyMKNK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-158) antibodyMKNK2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (Internal Region) antibodyMKNK2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-414) antibodyMKNK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))
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别名
- Mnk2
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背景
- Rabbit Anti-Mnk2 Polyclonal Antibody,MKNK2, GPRK7, MNK2, MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2,MKNK2 encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization.,MAP kinase-interacting serine threonine-protein kinase 2
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分子量
- observerd band 51kDa
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基因ID
- 2872
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UniProt
- Q9HBH9
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途径
- MAPK Pathway
抗原
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