MASP2 抗体 (AA 200-280)
Quick Overview for MASP2 抗体 (AA 200-280) (ABIN7219136)
抗原
See all MASP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-280
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原理
- MASP-2 Polyclonal Antibody
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特异性
- MASP-2 Polyclonal Antibody detects endogenous levels of MASP-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human MASP-2 at AA range: 200-280
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
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别名
- MASP-2
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背景
- Rabbit Anti-MASP-2 Polyclonal Antibody,MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2,MASP2 encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Mannan-binding lectin serine protease 2
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分子量
- observerd band 75kDa
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基因ID
- 10747
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UniProt
- O00187
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途径
- Complement System
抗原
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