HLA-DMA 抗体
Quick Overview for HLA-DMA 抗体 (ABIN7228250)
抗原
See all HLA-DMA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DMA Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DMA protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human DMA protein
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亚型
- IgG
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anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibody
HLA-DMA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibodyHLA-DMA 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 3F12-F11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) antibodyHLA-DMA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 27-233) antibodyHLA-DMA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) antibodyHLA-DMA 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 58-107) antibodyHLA-DMA 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibodyHLA-DMA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
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别名
- DMA
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背景
- Rabbit Anti-DMA Polyclonal Antibody,HLA class II histocompatibility antigen, DM alpha chain, MHC class II antigen DMA, Really interesting new gene 6 protein,HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. HLA-DMA (Major Histocompatibility Complex, Class II, DM Alpha) is a Protein Coding gene. Diseases associated with HLA-DMA include Rheumatoid Arthritis. Among its related pathways are Hematopoietic cell lineage and Allograft rejection.,DMA
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分子量
- observerd band 28kDa
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基因ID
- 3108
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UniProt
- P28067
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途径
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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