LRP1 抗体
Our Local Distributor
北京 101111
Quick Overview for LRP1 抗体 (ABIN7222264)
抗原
See all LRP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-LRP1 Polyclonal Antibody
-
特异性
- LRP1 Polyclonal Antibody detects endogenous levels of LRP1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human LRP1 around the non-phosphorylation site of S4520
-
亚型
- IgG
-
-
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (AA 20-270) antibody
LRP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (AA 20-155) antibodyLRP1 适用: 人 IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3F12E2 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (AA 4451-4545) antibodyLRP1 适用: 人, 小鼠 FACS, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (AA 4441-4544) antibodyLRP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (AA 1-292) antibodyLRP1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) antibodyLRP1 适用: 人 WB, IHC, FACS, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal A2Mralpha-2 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (C-Term) antibodyLRP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) antibodyKD Validated LRP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2130 unconjugated Recombinant Antibody
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) antibodyKD Validated LRP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4945 unconjugated Recombinant Antibody
anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (pSer4523) antibodyLRP1 适用: 人, 大鼠 FACS, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
-
别名
- LRP1
-
背景
- LRP1, A2MR, APR, Prolow-density lipoprotein receptor-related protein 1, LRP-1, Alpha-2-macroglobulin receptor, A2MR, Apolipoprotein E receptor, APOER, CD antigen CD91LRP1 encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
-
分子量
- 80kD
-
基因ID
- 4035
-
UniProt
- Q07954
-
途径
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
-
