LIG3 抗体 (AA 110-190)
Our Local Distributor
北京 101111
Quick Overview for LIG3 抗体 (AA 110-190) (ABIN7214588)
抗原
See all LIG3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 110-190
-
原理
- DNA Ligase III Polyclonal Antibody
-
特异性
- DNA Ligase III Polyclonal Antibody detects endogenous levels of DNA Ligase III protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human DNA Ligase III at AA range: 110-190
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
-
别名
- DNA Ligase III
-
背景
- Rabbit Anti-DNA Ligase III Polyclonal Antibody,LIG3, DNA ligase 3, DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3,LIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.,DNA ligase 3
-
分子量
- observerd band 100kDa
-
基因ID
- 3980
-
UniProt
- P49916
-
途径
- DNA Damage Repair
抗原
-