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JAK1 抗体

This 小鼠 单克隆 anti-JAK1 antibody (Clone 7G6) specifically detects JAK1 in IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7212172
发货至: 中国
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Quick Overview for JAK1 抗体 (ABIN7212172)

抗原

See all JAK1 抗体
JAK1 (Janus Kinase 1 (JAK1))

适用

  • 119
  • 87
  • 64
  • 2
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 99
  • 24
  • 1
  • 1
小鼠

克隆类型

  • 78
  • 47
单克隆

标记

  • 56
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
This JAK1 antibody is un-conjugated

应用范围

  • 95
  • 46
  • 29
  • 19
  • 17
  • 17
  • 16
  • 14
  • 11
  • 9
  • 3
  • 2
  • 2
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

7G6
  • 原理

    JAK1 Mouse Monoclonal Antibody (7G6)

    特异性

    JAK1 protein detects endogenous levels of JAK1.

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Synthetic Peptide of JAK1 at AA range of 960-1040

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    JAK1 (Janus Kinase 1 (JAK1))

    别名

    JAK1

    背景

    Mouse Anti-JAK1 Mouse Monoclonal Antibody (7G6),JAK1,JAK1 (Janus kinase 1) encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.,JAK1

    分子量

    observerd band 130kDa

    基因ID

    3716

    UniProt

    P23458

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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