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JAK1 抗体 (pTyr1022)

This anti-JAK1 antibody is a 兔 多克隆 antibody detecting JAK1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7205612
发货至: 中国

Quick Overview for JAK1 抗体 (pTyr1022) (ABIN7205612)

抗原

See all JAK1 抗体
JAK1 (Janus Kinase 1 (JAK1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This JAK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr1022

    原理

    JAK1 (phospho Tyr1022) Polyclonal Antibody

    特异性

    Phospho-JAK1 (Y1022) Polyclonal Antibody detects endogenous levels of JAK1 protein only when phosphorylated at Y1022.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human JAK1 Phospho-Tyr1022

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:50-1:200), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    JAK1 (Janus Kinase 1 (JAK1))

    别名

    JAK1

    背景

    Rabbit Anti-JAK1 (phospho Tyr1022) Polyclonal Antibody,JAK1, JAK1A, JAK1B, Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1,JAK1 encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase (Janus kinase 1) phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.,Tyrosine-protein kinase JAK1

    基因ID

    3716

    UniProt

    P23458

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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