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IL12RB2 抗体 (AA 270-350)

The 兔 多克隆 anti-IL12RB2 antibody (ABIN7228994) specifically detects IL12RB2 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7228994
发货至: 中国
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Quick Overview for IL12RB2 抗体 (AA 270-350) (ABIN7228994)

抗原

See all IL12RB2 抗体
IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

适用

人, 小鼠

宿主

  • 40
  • 11
  • 1

克隆类型

  • 43
  • 9
多克隆

标记

  • 28
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL12RB2 antibody is un-conjugated

应用范围

  • 34
  • 19
  • 17
  • 15
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 270-350

    原理

    I12R2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of I12R2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human I12R2 protein at AA range: 270-350

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

    别名

    I12R2

    背景

    Rabbit Anti-I12R2 Polyclonal Antibody,Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2,The Interleukin 12 Receptor Subunit Beta 2 encoded by IL12RB2 is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.,I12R2

    分子量

    observerd band 94kDa

    基因ID

    3595

    UniProt

    Q99665

    途径

    JAK/STAT Signaling
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