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Integrin beta 3 抗体 (pTyr785)

The 兔 多克隆 anti-Integrin beta 3 antibody is suitable to detect Integrin beta 3 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN7213194
发货至: 中国
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Quick Overview for Integrin beta 3 抗体 (pTyr785) (ABIN7213194)

抗原

See all Integrin beta 3 (ITGB3) 抗体
Integrin beta 3 (ITGB3)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Integrin beta 3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    pTyr785

    原理

    Rabbit Anti-Integrin β3 (phospho Tyr785) Polyclonal Antibody

    特异性

    Phospho-Integrin β3 (Y785) Polyclonal Antibody detects endogenous levels of Integrin β3 protein only when phosphorylated at Y785.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human Integrin beta3 Phospho-Tyr785

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF/ICC1:50-300,ELISA 1:2000-20000,IHC 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Integrin beta 3 (ITGB3)

    别名

    Integrin beta3

    背景

    ITGB3, GP3A, Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD antigen CD61The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

    分子量

    87kD

    基因ID

    3690

    UniProt

    P05106

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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