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IGF2R 抗体 (pSer2409)

This 兔 多克隆 anti-IGF2R antibody specifically detects IGF2R in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 猴 samples.
产品编号 ABIN7221718
发货至: 中国
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Quick Overview for IGF2R 抗体 (pSer2409) (ABIN7221718)

抗原

See all IGF2R 抗体
IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

适用

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人, 小鼠, 猴

宿主

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克隆类型

  • 59
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多克隆

标记

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This IGF2R antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer2409

    原理

    IGF-IIR (phospho Ser2409) Polyclonal Antibody

    特异性

    Phospho-IGF-IIR (S2409) Polyclonal Antibody detects endogenous levels of IGF-IIR protein only when phosphorylated at S2409.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human IGF-IIR Phospho-Ser2409

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

    别名

    IGF-IIR

    背景

    Rabbit Anti-IGF-IIR (phospho Ser2409) Polyclonal Antibody,IGF2R, MPRI, Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor,IGF2R encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele.,Cation-independent mannose-6-phosphate receptor

    分子量

    observerd band 300kDa

    基因ID

    3482

    UniProt

    P11717
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