HRH1 抗体 (pSer398)
Our Local Distributor
北京 101111
Quick Overview for HRH1 抗体 (pSer398) (ABIN7221568)
抗原
See all HRH1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer398
-
原理
- Histamine H1 Receptor (phospho Ser398) Polyclonal Antibody
-
特异性
- Phospho-Histamine H1 Receptor (S398) Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein only when phosphorylated at S398.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human Histamine H1 Receptor Phospho-Ser398
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- HRH1 (Histamine Receptor H1 (HRH1))
-
别名
- Histamine H1 Receptor
-
背景
- Rabbit Anti-Histamine H1 Receptor (phospho Ser398) Polyclonal Antibody,HRH1, Histamine H1 receptor, H1R, HH1R,Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The histamine receptor H1 encoded by HRH1 is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified.,Histamine H1 receptor
-
基因ID
- 3269
-
UniProt
- P35367
-
途径
- Regulation of Carbohydrate Metabolic Process
抗原
-