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HNF4A 抗体 (acLys106)

This 兔 多克隆 anti-HNF4A antibody specifically detects HNF4A in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7228948
发货至: 中国
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Quick Overview for HNF4A 抗体 (acLys106) (ABIN7228948)

抗原

See all HNF4A 抗体
HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 89
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多克隆

标记

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This HNF4A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    acLys106

    原理

    HNF-4α (Acetyl Lys106) Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of HNF-4α when Acetyl occurs at Lys106

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human HNF-4alpha (Acetyl Lys106) protein at AA range: 106

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

    别名

    HNF-4alpha

    背景

    Rabbit Anti-HNF-4α (Acetyl Lys106) Polyclonal Antibody,Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4,The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. HNF4A may play a role in development of the liver, kidney, and intestines. Mutations in HNF4A have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of HNF4A results in multiple transcript variants encoding several different isoforms. HNF4A (Hepatocyte Nuclear Factor 4 Alpha) is a Protein Coding gene. Diseases associated with HNF4A include Mody, Type I and Fanconi Renotubular Syndrome 4, With Maturity-Onset Diabetes Of The Young. Among its related pathways are Type II diabetes mellitus and Mesodermal Commitment Pathway.,HNF-4α

    分子量

    observerd band 55kDa

    基因ID

    3172

    UniProt

    P41235

    途径

    AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
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