CD42b 抗体 (Internal Region)
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Quick Overview for CD42b 抗体 (Internal Region) (ABIN7218316)
抗原
See all CD42b (GP1BA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- CD42b Polyclonal Antibody
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特异性
- CD42b Polyclonal Antibody detects endogenous levels of CD42b protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CD42b
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亚型
- IgG
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anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibody
GP1BA 适用: 人 WB, FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6H6H10 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibodyGP1BA 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6H6B11 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-291) antibodyGP1BA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-128) antibodyGP1BA 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 WB, FACS, ELISA, IP, ICC 宿主: 小鼠 Monoclonal AK2 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP1 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-282) antibodyGP1BA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 FACS 宿主: 小鼠 Monoclonal MM2-174 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
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别名
- CD42b
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背景
- Rabbit Anti-CD42b Polyclonal Antibody,GP1BA, Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b,Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013]GP1BA (Glycoprotein Ib Platelet Alpha Subunit) is a Protein Coding gene. Diseases associated with GP1BA include von willebrand disease, platelet-type and bernard-soulier syndrome, type a2. Among its related pathways are Platelet activation, signaling and aggregation and Formation of Fibrin Clot (Clotting Cascade). Gene Ontology (GO) annotations related to this gene include thrombin receptor activity. GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.,Platelet glycoprotein Ib alpha chain
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分子量
- observerd band 69kDa
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UniProt
- P07359
抗原
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