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GIT1 抗体 (AA 530-610)

This anti-GIT1 antibody is a 兔 多克隆 antibody detecting GIT1 in WB, ELISA 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7215060
发货至: 中国

Quick Overview for GIT1 抗体 (AA 530-610) (ABIN7215060)

抗原

See all GIT1 抗体
GIT1

适用

  • 86
  • 65
  • 50
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 114
  • 20

克隆类型

  • 96
  • 38
多克隆

标记

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  • 9
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GIT1 antibody is un-conjugated

应用范围

  • 101
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  • 27
  • 20
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  • 16
  • 13
  • 9
  • 8
  • 2
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 18
    • 15
    • 15
    • 15
    • 13
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 530-610

    原理

    GIT1 Polyclonal Antibody

    特异性

    GIT1 Polyclonal Antibody detects endogenous levels of GIT1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human GIT1 at AA range: 530-610

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GIT1

    别名

    GIT1

    背景

    Rabbit Anti-GIT1 Polyclonal Antibody,GIT1, ARF GTPase-activating protein GIT1, ARF GAP GIT1, Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1,ARF GTPase-activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK-interacting domain. The Arf-GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine morphology and formation---this is thought to occur through the Rac1/PAK1/LIMK/CFL1 pathway.,ARF GTPase-activating protein GIT1

    分子量

    observerd band 95kDa

    基因ID

    28964

    UniProt

    Q9Y2X7
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