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Gelsolin 抗体

This anti-Gelsolin antibody is a 兔 多克隆 antibody detecting Gelsolin in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7228646
发货至: 中国

Quick Overview for Gelsolin 抗体 (ABIN7228646)

抗原

See all Gelsolin (GSN) 抗体
Gelsolin (GSN)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 81
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多克隆

标记

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This Gelsolin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    GELS Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of GELS protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human GELS protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Gelsolin (GSN)

    别名

    GELS

    背景

    Rabbit Anti-GELS Polyclonal Antibody,Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin,Gelsolin encoded by GSN binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for GSN. GSN (Gelsolin) is a Protein Coding gene. Diseases associated with GSN include Amyloidosis, Finnish Type and Lattice Corneal Dystrophy Type Ii. Among its related pathways are Apoptosis and survival Caspase cascade and N-cadherin signaling events.,GELS

    分子量

    observerd band 86kDa

    基因ID

    2934

    UniProt

    P06396

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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