GPSM2 抗体
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北京 101111
Quick Overview for GPSM2 抗体 (ABIN7228762)
抗原
See all GPSM2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-GPSM2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of GPSM2 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human GPSM2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
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别名
- GPSM2
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背景
- G-protein-signaling modulator 2, Mosaic protein LGNThe protein encoded by GPSM2 belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. GPSM2 (G Protein Signaling Modulator 2) is a Protein Coding gene. Diseases associated with GPSM2 include Chudley-Mccullough Syndrome and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.
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分子量
- 75kD
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基因ID
- 29899
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UniProt
- P81274
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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