Frizzled5/8 抗体 (AA 10-90)
Quick Overview for Frizzled5/8 抗体 (AA 10-90) (ABIN7225248)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- Frizzled-5/8 Polyclonal Antibody
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特异性
- Frizzled-5/8 Polyclonal Antibody detects endogenous levels of Frizzled-5/8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Frizzled-5/8 at AA range: 10-90
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Frizzled5/8 (HYFZD5/8)
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别名
- Frizzled-5/8
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背景
- Rabbit Anti-Frizzled-5/8 Polyclonal Antibody,FZD5, C2orf31, Frizzled-5, Fz-5, hFz5, FzE5, FZD8, Frizzled-8, Fz-8, hFz8,This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.,Frizzled-5
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分子量
- observerd band 75kDa
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基因ID
- 8325, 7855
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途径
- WNT signaling
抗原
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