FZD7 抗体 (AA 20-100)
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Quick Overview for FZD7 抗体 (AA 20-100) (ABIN7214956)
抗原
See all FZD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-100
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原理
- Frizzled-7 Polyclonal Antibody
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特异性
- Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Frizzled-7 at AA range: 20-100
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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别名
- Frizzled-7
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背景
- Rabbit Anti-Frizzled-7 Polyclonal Antibody,FZD7, Frizzled-7, Fz-7, hFz7, FzE3,Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Frizzled-7 contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.,Frizzled-7
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分子量
- observerd band 64kDa
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基因ID
- 8324
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UniProt
- O75084
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途径
- WNT signaling, Stem Cell Maintenance
抗原
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