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FKBP1A 抗体

This 兔 多克隆 anti-FKBP1A antibody specifically detects FKBP1A in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7228536
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FKBP1A 抗体 (ABIN7228536)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

  • 68
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  • 6
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  • 1
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人, 小鼠, 大鼠

宿主

  • 65
  • 11

克隆类型

  • 46
  • 30
多克隆

标记

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  • 8
  • 8
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  • 2
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This FKBP1A antibody is un-conjugated

应用范围

  • 50
  • 22
  • 20
  • 20
  • 14
  • 12
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    FKB1A Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of FKB1A protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human FKB1A protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKB1A

    背景

    Rabbit Anti-FKB1A Polyclonal Antibody,Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase,Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,FKB1A

    分子量

    observerd band 11kDa

    基因ID

    2280

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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