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FKBP1A 抗体

This 兔 多克隆 antibody specifically detects FKBP1A in IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7259707
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FKBP1A 抗体 (ABIN7259707)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

  • 69
  • 39
  • 32
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 65
  • 12

克隆类型

  • 46
  • 31
多克隆

标记

  • 33
  • 8
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
This FKBP1A antibody is un-conjugated

应用范围

  • 52
  • 21
  • 20
  • 20
  • 15
  • 12
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human FKBP1A (NP_463460.1).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKBP1A

    背景

    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

    基因ID

    2280

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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