FKBP1A 抗体 (C-Term)
(2 references)-
- 抗原 See all FKBP1A 抗体
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
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抗原表位
- AA 55-83, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FKBP1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B, Rb
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the C-terminal region of human FKBP1A.
- 克隆位点
- RB19307
- 亚型
- Ig Fraction
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anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibody
FKBP1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5-A12 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibodyFKBP1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-103) antibodyFKBP1A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibodyFKBP1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibodyFKBP1A 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (N-Term) antibodyFKBP1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 43-74) antibodyFKBP1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, (2008) (PubMed).
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: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
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- 抗原
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
- 别名
- FKBP1A (FKBP1A 产品)
- 别名
- 12kDa antibody, FKBP12 antibody, FKBP12-T1 antibody, FKBP12-T2 antibody, Fkbp antibody, Fkbp1 antibody, mFKBP1 antibody, mFKBP12 antibody, FKBP-12 antibody, FKBP-1A antibody, FKBP1 antibody, Rotamase antibody, Fkbp12 antibody, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 antibody, ATFKBP12 antibody, FK506-binding protein 12 antibody, IMMUNOPHILIN antibody, MSJ1.19 antibody, MSJ1_19 antibody, PKC12 antibody, PKCI2 antibody, PPIASE antibody, FKBP1B antibody, Fkbp2 antibody, fj02g10 antibody, zgc:73373 antibody, wu:fj02g10 antibody, FKBP1A antibody, Bmfkbp13 antibody, zgc:103752 antibody, FK506 binding protein 1a antibody, FK506 binding protein 1A antibody, FK506-binding protein antibody, FK506-binding protein 12 antibody, FK506 binding protein 1Aa antibody, FK506 binding protein 1C antibody, FK506-binding protein 59 antibody, FK506 binding protein like antibody, FK506 binding protein 1A L homeolog antibody, FK506 binding protein 1Ab antibody, Fkbp1a antibody, FKBP1A antibody, Fkbp12 antibody, FKBP12 antibody, fkbp1aa antibody, FKBP1C antibody, EHI_180160 antibody, LOC5573443 antibody, Fkbp13 antibody, FKBPL antibody, fkbp1a.L antibody, fkbp1ab antibody
- 背景
- FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
- 分子量
- 11951
- NCBI登录号
- NP_000792, NP_463460
- UniProt
- P62942
- 途径
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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