Fibulin 5 抗体 (AA 140-220)
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Quick Overview for Fibulin 5 抗体 (AA 140-220) (ABIN7214900)
抗原
See all Fibulin 5 (FBLN5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-220
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原理
- Fibulin-5 Polyclonal Antibody
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特异性
- Fibulin-5 Polyclonal Antibody detects endogenous levels of Fibulin-5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Fibulin-5 at AA range: 140-220
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Fibulin 5 (FBLN5)
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别名
- Fibulin-5
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背景
- Rabbit Anti-Fibulin-5 Polyclonal Antibody,FBLN5, DANCE, Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50,Fibulin-5 encoded by FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).,Fibulin-5
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分子量
- observerd band 50kDa
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基因ID
- 10516
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UniProt
- Q9UBX5
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途径
- SARS-CoV-2 Protein Interactome
抗原
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