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FGFRL1 抗体 (AA 130-210)

This anti-FGFRL1 antibody is a 兔 多克隆 antibody detecting FGFRL1 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7223224
发货至: 中国

Quick Overview for FGFRL1 抗体 (AA 130-210) (ABIN7223224)

抗原

See all FGFRL1 抗体
FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

适用

  • 48
  • 14
  • 4
  • 1
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  • 1
人, 小鼠

宿主

  • 50
  • 1
  • 1

克隆类型

  • 50
  • 2
多克隆

标记

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  • 4
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  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FGFRL1 antibody is un-conjugated

应用范围

  • 39
  • 18
  • 17
  • 13
  • 13
  • 7
  • 5
  • 5
  • 3
  • 2
  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 5
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-210

    原理

    FGFR-5 Polyclonal Antibody

    特异性

    FGFR-5 Polyclonal Antibody detects endogenous levels of FGFR-5 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human FGFR-5 at AA range: 130-210

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

    别名

    FGFR-5

    背景

    Rabbit Anti-FGFR-5 Polyclonal Antibody,FGFRL1, FGFR5, FHFR, Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, FGFR-5,The protein encoded by FGFRL1 (fibroblast growth factor receptor-like 1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for FGFRL1.,Fibroblast growth factor receptor-like 1

    分子量

    observerd band 54kDa

    基因ID

    53834

    UniProt

    Q8N441

    途径

    RTK signaling
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