FARP2 抗体 (AA 300-380)
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北京 101111
Quick Overview for FARP2 抗体 (AA 300-380) (ABIN7214904)
抗原
See all FARP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-380
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原理
- FIR Polyclonal Antibody
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特异性
- FIR Polyclonal Antibody detects endogenous levels of FIR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human FIR at AA range: 300-380
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亚型
- IgG
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anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (AA 261-550) antibody
FARP2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (Internal Region) antibodyFARP2 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) antibodyFARP2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (AA 360-448) antibodyFARP2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) antibodyFARP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (Internal Region) antibodyFARP2 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (Internal Region) antibodyFARP2 适用: 人, 小鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (AA 1-647) antibodyFARP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
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别名
- FIR
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背景
- Rabbit Anti-FIR Polyclonal Antibody,FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3,FARP2 is a Protein Coding gene. FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion. Diseases associated with FARP2 include verheij syndrome and aarskog-scott syndrome. Among its related pathways are Developmental Biology and Adherens junction. GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and Rac guanyl-nucleotide exchange factor activity. An important paralog of this gene is FRMD3.,FERM RhoGEF and pleckstrin domain-containing protein 2
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分子量
- observerd band 119kDa
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基因ID
- 9855
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UniProt
- O94887
抗原
-
