FARP2 抗体 (AA 601-700)
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- 抗原 See all FARP2 抗体
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
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抗原表位
- AA 601-700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FARP2 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FARP2
- 亚型
- IgG
- Top Product
- Discover our top product FARP2 Primary Antibody
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anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (AA 261-550) antibody
FARP2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (Internal Region) antibodyFARP2 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) antibodyFARP2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (AA 360-448) antibodyFARP2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) antibodyFARP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (Internal Region) antibodyFARP2 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (Internal Region) antibodyFARP2 适用: 人, 小鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2) (AA 1-647) antibodyFARP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
- 别名
- FARP2 (FARP2 产品)
- 别名
- FARP2 antibody, wu:fc23d05 antibody, wu:fp25d09 antibody, MGC131000 antibody, FIR antibody, FRG antibody, PLEKHC3 antibody, AI465173 antibody, BC009153 antibody, D030026M03Rik antibody, Fir antibody, mKIAA0793 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 antibody, FERM, RhoGEF and pleckstrin domain protein 2 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog antibody, FARP2 antibody, farp2 antibody, farp2.L antibody, Farp2 antibody
- 背景
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Synonyms: FARP 2, FERM, FGD1 related Cdc42 GEF, FIR, FRG, KIAA0793, PLEKHC3, RhoGEF and pleckstrin domain protein 2, FARP2_HUMAN.
Background: FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
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