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FARP2 抗体 (AA 601-700) (Biotin)

FARP2 适用: 人 ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1391401
发货至: 中国
  • 抗原 See all FARP2 抗体
    FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
    抗原表位
    • 14
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-700
    适用
    • 39
    • 16
    • 2
    宿主
    • 39
    • 1
    克隆类型
    • 40
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FARP2 antibody is conjugated to Biotin
    应用范围
    • 14
    • 13
    • 13
    • 12
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FARP2
    亚型
    IgG
    Top Product
    Discover our top product FARP2 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
    别名
    FARP2 (FARP2 产品)
    别名
    FARP2 antibody, wu:fc23d05 antibody, wu:fp25d09 antibody, MGC131000 antibody, FIR antibody, FRG antibody, PLEKHC3 antibody, AI465173 antibody, BC009153 antibody, D030026M03Rik antibody, Fir antibody, mKIAA0793 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 antibody, FERM, RhoGEF and pleckstrin domain protein 2 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog antibody, FARP2 antibody, farp2 antibody, farp2.L antibody, Farp2 antibody
    背景

    Synonyms: FARP 2, FERM, FGD1 related Cdc42 GEF, FIR, FRG, KIAA0793, PLEKHC3, RhoGEF and pleckstrin domain protein 2, FARP2_HUMAN.

    Background: FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.

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