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FANCD2 抗体

This 兔 多克隆 anti-FANCD2 antibody specifically detects FANCD2 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7214862
发货至: 中国
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Quick Overview for FANCD2 抗体 (ABIN7214862)

抗原

See all FANCD2 抗体
FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

适用

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人, 小鼠, 大鼠

宿主

  • 79
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克隆类型

  • 60
  • 20
多克隆

标记

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This FANCD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    FANCD2 Polyclonal Antibody

    特异性

    FANCD2 Polyclonal Antibody detects endogenous levels of FANCD2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human FANCD2 around the non-phosphorylation site of S222

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

    别名

    FANCD2

    背景

    Rabbit Anti-FANCD2 Polyclonal Antibody,FANCD2, FACD, Fanconi anemia group D2 protein, Protein FACD2,The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. FANCD2 encodes the protein for complementation group D2. Fanconi anemia group D2 protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.,Fanconi anemia group D2 protein

    分子量

    observerd band 166kDa

    基因ID

    2177

    UniProt

    Q9BXW9

    途径

    DNA Damage Repair
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