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FANCA 抗体 (pSer1149)

This 兔 多克隆 anti-FANCA antibody specifically detects FANCA in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7220418
发货至: 中国
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Quick Overview for FANCA 抗体 (pSer1149) (ABIN7220418)

抗原

See all FANCA 抗体
FANCA (Fanconi Anemia Group A Protein (FANCA))

适用

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宿主

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克隆类型

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多克隆

标记

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This FANCA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pSer1149

    原理

    FANCA (phospho Ser1149) Polyclonal Antibody

    特异性

    Phospho-FANCA (S1149) Polyclonal Antibody detects endogenous levels of FANCA protein only when phosphorylated at S1149.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human FANCA Phospho-Ser1149

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FANCA (Fanconi Anemia Group A Protein (FANCA))

    别名

    FANCA

    背景

    Rabbit Anti-FANCA (phospho Ser1149) Polyclonal Antibody,FANCA, FAA, FACA, FANCH, Fanconi anemia group A protein, Protein FACA,The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.,Fanconi anemia group A protein

    分子量

    observerd band 162kDa

    基因ID

    2175

    UniProt

    O15360

    途径

    DNA Damage Repair
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