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p300 抗体 (Internal Region)

This 兔 多克隆 anti-p300 antibody specifically detects p300 in WB, ELISA, IHC (p) 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7226646
发货至: 中国
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Quick Overview for p300 抗体 (Internal Region) (ABIN7226646)

抗原

See all p300 (EP300) 抗体
p300 (EP300) (E1A Binding Protein P300 (EP300))

适用

  • 100
  • 46
  • 26
  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 93
  • 11

克隆类型

  • 94
  • 10
多克隆

标记

  • 62
  • 7
  • 6
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This p300 antibody is un-conjugated

应用范围

  • 70
  • 52
  • 43
  • 21
  • 17
  • 15
  • 15
  • 13
  • 12
  • 9
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 36
    • 13
    • 9
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    原理

    p300 Polyclonal Antibody

    特异性

    P300 Polyclonal Antibody detects endogenous levels of p300 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human p300

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    p300 (EP300) (E1A Binding Protein P300 (EP300))

    别名

    p300

    背景

    Rabbit Anti-p300 Polyclonal Antibody,EP300, P300, Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300,EP300 (E1A binding protein p300) encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.,Histone acetyltransferase p300

    分子量

    observerd band 300kDa

    基因ID

    2033

    UniProt

    Q09472

    途径

    p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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