Dual Specificity Phosphatase 3 (DUSP3) (C-Term) 抗体
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Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (C-Term) 抗体 (ABIN7217992)
抗原
See all Dual Specificity Phosphatase 3 (DUSP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- VHR Polyclonal Antibody
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特异性
- VHR Polyclonal Antibody detects endogenous levels of VHR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human VHR
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亚型
- IgG
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anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibody
DUSP3 适用: 人 WB 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) antibodyDUSP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 1-30), (N-Term) antibodyDUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06032 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) antibodyDUSP3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (N-Term) antibodyDUSP3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 157-185), (C-Term) antibodyDUSP3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB5730 unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (C-Term) antibodyDUSP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 3 (DUSP3) (AA 14-96) antibodyDUSP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Dual Specificity Phosphatase 3 (DUSP3)
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别名
- VHR
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背景
- Rabbit Anti-VHR Polyclonal Antibody,DUSP3, VHR, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, VHR,Dual specificity protein phosphatase 3 encoded by DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.,Dual specificity protein phosphatase 3
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分子量
- observerd band 21kDa
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基因ID
- 1845
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UniProt
- P51452
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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