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Diazepam Binding Inhibitor 抗体 (Internal Region)

The 兔 多克隆 anti-Diazepam Binding Inhibitor antibody is suitable to detect Diazepam Binding Inhibitor in samples from 人. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7213444
发货至: 中国
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Quick Overview for Diazepam Binding Inhibitor 抗体 (Internal Region) (ABIN7213444)

抗原

See all Diazepam Binding Inhibitor (DBI) 抗体
Diazepam Binding Inhibitor (DBI)

适用

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宿主

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克隆类型

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多克隆

标记

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This Diazepam Binding Inhibitor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    原理

    ACBP Polyclonal Antibody

    特异性

    ACBP Polyclonal Antibody detects endogenous levels of ACBP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human ACBP

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Diazepam Binding Inhibitor (DBI)

    别名

    ACBP

    背景

    Rabbit Anti-ACBP Polyclonal Antibody,DBI, Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EP,DBI encodes diazepam binding inhibitor (diazepam binding inhibitor, acyl-CoA binding protein), a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for DBI.,Acyl-CoA-binding protein

    基因ID

    1622

    UniProt

    P07108
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