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Diazepam Binding Inhibitor 抗体 (AA 2-87)

DBI 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886558
发货至: 中国
  • 抗原 See all Diazepam Binding Inhibitor (DBI) 抗体
    Diazepam Binding Inhibitor (DBI)
    抗原表位
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 2-87
    适用
    • 34
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 37
    • 2
    克隆类型
    • 38
    • 1
    多克隆
    标记
    • 20
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Diazepam Binding Inhibitor antibody is un-conjugated
    应用范围
    • 28
    • 17
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Acyl-CoA-binding protein(DBI) detection. Tested with WB, IHC-P in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Acyl-CoA-binding protein(DBI) detection. Tested with WB, IHC-P in Human.
    Gene Name: diazepam binding inhibitor, acyl-CoA binding protein
    Protein Name: Acyl-CoA-binding protein
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse and rat DBI.
    亚型
    IgG
    Top Product
    Discover our top product DBI Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Diazepam Binding Inhibitor (DBI)
    别名
    DBI (DBI 产品)
    别名
    ACBD1 antibody, ACBP antibody, CCK-RP antibody, EP antibody, dbib antibody, DBI antibody, wu:fb63e10 antibody, zgc:56108 antibody, zgc:77734 antibody, Acbp antibody, endozepine antibody, Acoabp3 antibody, Ep antibody, Odn antibody, RNACOABP3 antibody, Ttn antibody, acbd1 antibody, acbp antibody, cck-rp antibody, dbi antibody, dbi-a antibody, dbi-b antibody, dbia antibody, diazepam binding inhibitor, acyl-CoA binding protein antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog antibody, diazepam-binding inhibitor antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) antibody, acyl-CoA-binding protein antibody, diazepam binding inhibitor antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog antibody, DBI antibody, dbi.S antibody, dbi antibody, LOC706367 antibody, Dbi antibody, dbi.L antibody
    背景
    Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

    Synonyms: ACBD 1 | ACBD1 | ACBP | CCK RP | CCKRP | DBI | Endozepine | EP | P07108
    基因ID
    1622
    UniProt
    P07108
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