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Diazepam Binding Inhibitor 抗体 (N-Term)

DBI 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777771
发货至: 中国
  • 抗原 See all Diazepam Binding Inhibitor (DBI) 抗体
    Diazepam Binding Inhibitor (DBI)
    抗原表位
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠
    宿主
    • 37
    • 2
    克隆类型
    • 38
    • 1
    多克隆
    标记
    • 20
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Diazepam Binding Inhibitor antibody is un-conjugated
    应用范围
    • 28
    • 16
    • 16
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF
    预测反应
    Cow: 86%, Dog: 79%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against DBI. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DBI
    Top Product
    Discover our top product DBI Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 87 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Diazepam Binding Inhibitor (DBI)
    别名
    DBI (DBI 产品)
    别名
    ACBD1 antibody, ACBP antibody, CCK-RP antibody, EP antibody, dbib antibody, DBI antibody, wu:fb63e10 antibody, zgc:56108 antibody, zgc:77734 antibody, Acbp antibody, endozepine antibody, Acoabp3 antibody, Ep antibody, Odn antibody, RNACOABP3 antibody, Ttn antibody, acbd1 antibody, acbp antibody, cck-rp antibody, dbi antibody, dbi-a antibody, dbi-b antibody, dbia antibody, diazepam binding inhibitor, acyl-CoA binding protein antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog antibody, diazepam-binding inhibitor antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) antibody, acyl-CoA-binding protein antibody, diazepam binding inhibitor antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog antibody, DBI antibody, dbi.S antibody, dbi antibody, LOC706367 antibody, Dbi antibody, dbi.L antibody
    背景
    DBI is diazepam binding inhibitor. The protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. DBI is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: ACBD1, ACBP, CCK-RP, EP, MGC70414
    Protein Interaction Partner: UBC, MAP1LC3B, NSFL1C, DUSP23, NIPSNAP1, RAD23B, RAD23A, GSK3B, UBXN2A, TSPO, PPCDC,
    Protein Size: 87
    分子量
    10 kDa
    基因ID
    1622
    NCBI登录号
    NM_001079862, NP_001073331
    UniProt
    P07108
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