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CTLA4 抗体 (AA 41-90)

This anti-CTLA4 antibody is a 兔 多克隆 antibody detecting CTLA4 in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7227690
发货至: 中国

Quick Overview for CTLA4 抗体 (AA 41-90) (ABIN7227690)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 41-90

    原理

    CD152 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CD152

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CD152 protein at AA range: 41-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CD152

    背景

    Rabbit Anti-CD152 Polyclonal Antibody,Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD antigen CD152,CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in CTLA4 have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.,CD152

    基因ID

    1493

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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