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CISH 抗体 (AA 30-90)

The 兔 多克隆 anti-CISH antibody (ABIN7227912) specifically detects CISH in IHC, IF 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7227912
发货至: 中国
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北京 101111
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Quick Overview for CISH 抗体 (AA 30-90) (ABIN7227912)

抗原

See all CISH 抗体
CISH (Cytokine Inducible SH2-Containing Protein (CISH))

适用

  • 25
  • 18
  • 16
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 25
  • 1

克隆类型

  • 26
多克隆

标记

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CISH antibody is un-conjugated

应用范围

  • 15
  • 7
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  • 4
  • 4
  • 2
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-90

    原理

    Rabbit Anti-CIS Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CIS

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human CIS protein at AA range: 30-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CISH (Cytokine Inducible SH2-Containing Protein (CISH))

    别名

    CIS

    背景

    Cytokine-inducible SH2-containing protein, CIS, CIS-1, Protein G18, Suppressor of cytokine signaling, SOCSThe protein encoded by CISH contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of CISH can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for CISH. CISH (Cytokine Inducible SH2 Containing Protein) is a Protein Coding gene. Diseases associated with CISH include Bacteremia and Malaria. Among its related pathways are Jak-STAT signaling pathway (KEGG) and IL-2 Signaling Pathway.

    基因ID

    1154

    UniProt

    Q9NSE2

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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