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CISH 抗体 (AA 1-257)

The 兔 多克隆 anti-CISH antibody is suitable to detect CISH in samples from 人. It has been validated for IHC 和 ELISA.
产品编号 ABIN7149303
发货至: 中国
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Room 801-803
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Quick Overview for CISH 抗体 (AA 1-257) (ABIN7149303)

抗原

See all CISH 抗体
CISH (Cytokine Inducible SH2-Containing Protein (CISH))

适用

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宿主

  • 36
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克隆类型

  • 37
多克隆

标记

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This CISH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 1-257

    原理

    CISH Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Cytokine-inducible SH2-containing protein (1-257AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CISH (Cytokine Inducible SH2-Containing Protein (CISH))

    别名

    CISH

    背景

    Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    Aliases: BACTS2 antibody, cis 1 antibody, CIS antibody, CIS-1 antibody, CIS1 antibody, Cish antibody, CISH_HUMAN antibody, Cytokine inducible inhibitor of signaling type 1B antibody, Cytokine inducible SH2 containing protein antibody, Cytokine-inducible SH2-containing protein antibody, G18 antibody, Protein G18 antibody, SOCS antibody, Suppressor of cytokine signaling antibody

    UniProt

    Q9NSE2

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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