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CISH 抗体 (AA 17-130)

The 兔 多克隆 anti-CISH antibody (ABIN7266663) specifically detects CISH in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7266663
发货至: 中国
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Quick Overview for CISH 抗体 (AA 17-130) (ABIN7266663)

抗原

See all CISH 抗体
CISH (Cytokine Inducible SH2-Containing Protein (CISH))

适用

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  • 19
  • 17
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  • 1

宿主

  • 25
  • 1

克隆类型

  • 26
多克隆

标记

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This CISH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 4
    • 3
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    • 1
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    AA 17-130

    原理

    CISH Rabbit pAb

    序列

    TGQRPLWAPS LELPKPVMQP LPAGAFLEEV AEGTPAQTES EPKVLDPEED LLCIAKTFSY LRESGWYWGS ITASEARQHL QKMPEGTFLV RDSTHPSYLF TLSVKTTRGP TNVR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human CISH (NP_659508.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CISH (Cytokine Inducible SH2-Containing Protein (CISH))

    别名

    CISH

    背景

    The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.,CISH,BACTS2,CIS,CIS-1,G18,SOCS,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,CISH

    分子量

    28kDa/29kDa/30kDa

    基因ID

    1154

    UniProt

    Q9NSE2

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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