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CYBB 抗体 (Internal Region)

This 兔 多克隆 anti-CYBB antibody specifically detects CYBB in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7218298
发货至: 中国
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Quick Overview for CYBB 抗体 (Internal Region) (ABIN7218298)

抗原

See all CYBB 抗体
CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

适用

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宿主

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克隆类型

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多克隆

标记

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This CYBB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    原理

    gp91-phox Polyclonal Antibody

    特异性

    Gp91-phox Polyclonal Antibody detects endogenous levels of gp91-phox protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human gp91-phox

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

    别名

    gp91-phox

    背景

    Rabbit Anti-gp91-phox Polyclonal Antibody,CYBB, NOX2, Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, NADPH oxidase 2Neutrophil cytochrome b 91 kDa polypeptide, Superoxide-generating NADPH oxidase heavy chain subunit, gp91-1, gp91-phox, p22 phagocyte B-cytochrome,Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.,Cytochrome b-245 heavy chain

    分子量

    observerd band 70kDa

    基因ID

    1536

    UniProt

    P04839
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